Guidance

Medicines eligible for Northern Ireland MHRA Authorised Route

Sets out medicines that can be moved to Northern Ireland to meet patient need.

From:
Department of Health and Social Care
Published
16 December 2021
Last updated
413 April 2023 — See all updates

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List of medicines that can be moved through NIMAR

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This document lists the medicines eligible for supply through the Northern Ireland MHRA Authorised Route (NIMAR).

From 1 January 2022, the listed medicines may be dispatched from Great Britain to Northern Ireland on the basis of the medicine’s authorisation in Great Britain.

This list is maintained and published in accordance with regulation 167B (list of NIMAR products) of the Human Medicines Regulations 2012 (SI 2012/1916, as amended).

Published 16 December 2021
Last updated 413 April 2023 + show all updates

  1. Added: (Pelmeg 6mg/0.6ml solution for injection pre-filled syringes) Pegfilgrastim 6mg/0.6ml solution for injection pre-filled syringes. Removed: (Benlysta 200mg/1ml solution for injection pre-filled pens) Belimumab 200mg/1ml solution for injection pre-filled disposable devices. Changed: Imatinib 100mg tablets to (Glivec 100 mg tablets) Imatinib 100mg tablets and Imatinib 400mg tablets to (Glivec 400 mg tablets) Imatinib 400mg tablets.

  2. The following products have been added to the list: (Benlysta 200mg/1ml solution for injection pre-filled pens) Belimumab 200mg/1ml solution for injection pre-filled disposable devices, (Toujeo 300units/ml solution for injection 3ml pre-filled DoubleStar pens) Insulin glargine 300units/ml solution for injection 3ml pre-filled disposable devices, and (Orkambi 75 mg/94 mg granules in sachet) Lumacaftor 75 mg/Ivacaftor 94 mg granules sachet. The following product has been removed from the list: (Remsima 100mg powder for concentrate for solution for infusion vials) Infliximab 100mg powder for solution for infusion vials.

  3. The following products have been added to the list: Buprenorphine 128mg/0.36ml prolonged-release solution for injection pre-filled syringes; Buprenorphine 160mg/0.45ml prolonged-release solution for injection pre-filled syringes; Buprenorphine 16mg/0.32ml prolonged-release solution for injection pre-filled syringes; Buprenorphine 24mg/0.48ml prolonged-release solution for injection pre-filled syringes; Buprenorphine 32mg/0.64ml prolonged-release solution for injection pre-filled syringes; Buprenorphine 64mg/0.18ml prolonged-release solution for injection pre-filled syringes; Buprenorphine 8mg/0.16ml prolonged-release solution for injection pre-filled syringes; Buprenorphine 96mg/0.27ml prolonged-release solution for injection pre-filled syringes

  4. Added: (Remsima 120mg/1ml solution for injection pre-filled pens) Infliximab 120mg/1ml solution for injection pre-filled disposable devices.

  5. Added: (Byetta 10micrograms/0.04ml solution for injection 2.4ml pre-filled pens) Exenatide 10micrograms/0.04ml solution for injection 2.4ml pre-filled disposable devices; (Byetta 5micrograms/0.02ml solution for injection 1.2ml pre-filled pens) Exenatide 5micrograms/0.02ml solution for injection 1.2ml pre-filled disposable devices; Hydroxycarbamide 100mg tablets.

  6. Added: Avalglucosidase alfa 100mg powder for solution for infusion vials; Etoposide 100mg/5ml solution for infusion vials. Removed: (Truxima 500mg/50ml concentrate for solution for infusion vials) Rituximab 500mg/50ml solution for infusion vials.

  7. Added: Canagliflozin 100mg tablets and Canagliflozin 300mg tablets. Removed (Toujeo 300units/ml solution for injection 3ml pre-filled DoubleStar pens) Insulin glargine 300units/ml solution for injection 3ml pre-filled disposable devices; Upadacitinib 45mg modified-release tablets; and (Plavix 75mg tablets) Clopidogrel 75mg tablets.

  8. Updated to add (Plavix 75mg tablets) Clopidogrel 75mg tablets.

  9. Removed from the list: Patisiran 2 mg/ml concentrate for solution for infusion. Added to the list: Methotrexate 1g/10ml solution for injection vials and Methotrexate 5g/50ml solution for infusion vials.

  10. Updated to add 'Nuvaxovid COVID-19 Vaccine (recombinant, adjuvanted) dispersion for injection' and to remove 'Cell-based quadrivalent influenza vaccine (surface antigen, inactivated) suspension for injection 0.5ml pre-filled syringes'.

  11. The following medicine has been added to the list: (Toujeo 300units/ml solution for injection 3ml pre-filled DoubleStar pens) Insulin glargine 300units/ml solution for injection 3ml pre-filled disposable devices, and the following 6 medicines have been removed from the list: (HyQvia 10g/100ml solution for infusion and 5ml vials) Normal immunoglobulin human 10g/100ml solution for infusion vials and Recombinant human hyaluronidase solution for infusion 5ml vials, (HyQvia 2.5g/25ml solution for infusion and 1.25ml vials) Normal immunoglobulin human 2.5g/25ml solution for infusion vials and Recombinant human hyaluronidase solution for infusion 1.25ml vials, (HyQvia 30g/300ml solution for infusion and 15ml vials) Normal immunoglobulin human 30g/300ml solution for infusion vials and Recombinant human hyaluronidase solution for infusion 15ml vials, (HyQvia 5g/50ml solution for infusion and 2.5ml vials) Normal immunoglobulin human 5g/50ml solution for infusion vials and Recombinant human hyaluronidase solution for infusion 2.5ml vials, (Fotivda 1340microgram capsules) Tivozanib 1340microgram capsules, and (Fotivda 890microgram capsules) Tivozanib 890microgram capsules.

  12. Changed '(Esperoct 5000 unit powder and solvent for solution for injection vials) Turoctocog alfa pegol 500 unit powder and solvent for solution for injection vials' to: '(Esperoct 500 unit powder and solvent for solution for injection vials) Turoctocog alfa pegol 500 unit powder and solvent for solution for injection vials'. Added the following medicines to the list: Ibandronic acid 50mg tablets; Lixisenatide 20mg / 0.2ml solution for injection 3ml pre-filled disposable devices; Potassium citrate 282mg / Potassium bicarbonate 527mg modified-release granules sachets sugar free; and Potassium citrate 847mg / Potassium bicarbonate 1.582g modified-release granules sachets sugar free.

  13. 28 products have been added to the list: Normal immunoglobulin human 2.5g/25ml solution for infusion vials and Recombinant human hyaluronidase solution for infusion 1.25ml vials; Normal immunoglobulin human 5g/50ml solution for infusion vials and Recombinant human hyaluronidase solution for infusion 2.5ml vials; Normal immunoglobulin human 10g/100ml solution for infusion vials and Recombinant human hyaluronidase solution for infusion 5ml vials; Normal immunoglobulin human 30g/300ml solution for infusion vials and Recombinant human hyaluronidase solution for infusion 15ml vials; Naloxone 1.8mg/0.1ml nasal spray unit dose; Glycopyrronium 7.2micrograms/dose / Formoterol 5micrograms/dose inhaler CFC free; Interferon beta-1b 300microgram powder and solvent for solution for injection vials; Saxagliptin 2.5mg / Metformin 1g tablets; Saxagliptin 5mg / Dapagliflozin 10mg tablets; Eptacog alfa (activated) 1mg (50,000unit) powder and solvent for solution for injection pre-filled syringes; Eptacog alfa (activated) 2mg (100,000unit) powder and solvent for solution for injection pre-filled syringes; Eptacog alfa (activated) 5mg (250,000unit) powder and solvent for solution for injection pre-filled syringes; Eptacog alfa (activated) 8mg (400,000unit) powder and solvent for solution for injection pre-filled syringes; Turoctocog alfa pegol 1,000unit powder and solvent for solution for injection vials; Turoctocog alfa pegol 1,500unit powder and solvent for solution for injection vials; Turoctocog alfa pegol 2,000unit powder and solvent for solution for injection vials; Turoctocog alfa pegol 3,000unit powder and solvent for solution for injection vials; Turoctocog alfa pegol 500unit powder and solvent for solution for injection vials; Turoctocog alfa 250unit powder and solvent for solution for injection vials; Turoctocog alfa 500unit powder and solvent for solution for injection vials; Turoctocog alfa 1,000unit powder and solvent for solution for injection vials; Turoctocog alfa 1,500unit powder and solvent for solution for injection vials; Turoctocog alfa 2,000unit powder and solvent for solution for injection vials; Turoctocog alfa 3,000unit powder and solvent for solution for injection vials; Catridecacog 2,500unit powder and solvent for solution for injection vials; Nonacog beta pegol 1,000unit powder and solvent for solution for injection vials; Nonacog beta pegol 2,000unit powder and solvent for solution for injection vials; Nonacog beta pegol 500unit powder and solvent for solution for injection vials

  14. Added 2 products to the list: Omalizumab 75mg/0.5ml solution for injection pre-filled syringes and Oxybutynin 3.9mg/24 hours transdermal patches.

  15. Added: (NovoRapid FlexTouch 100units/ml solution for injection 3ml pre-filled pens) Insulin aspart 100units/ml solution for injection 3ml pre-filled disposable devices; Erenumab 140mg/1ml solution for injection pre-filled disposable devices; Erenumab 70mg/1ml solution for injection pre-filled disposable devices; Sarilumab 150mg/1.14ml solution for injection pre-filled syringes; Sarilumab 200mg/1.14ml solution for injection pre-filled syringes; Sarilumab 150mg/1.14ml solution for injection pre-filled disposable devices; Sarilumab 200mg/1.14ml solution for injection pre-filled disposable devices; Mitomycin 40mg powder and solvent for intravesical solution vials; Imatinib 100mg tablets; Imatinib 400mg tablets. Removed: Bimatoprost 300micrograms/ml eye drops 0.4ml unit dose preservative free. Changed: Simulect 10mg powder and solvent forsolution for injection vials (1 vial) to Basiliximab 10mg powder and solvent forsolution for injection vials; Simulect 20mg powder and solvent for solution for injection vials to Basiliximab 20mg powder and solvent for solution for injection vials.

  16. Added: Conestat alfa 2,100 unit powder and solvent for solution for injection vials.

  17. Added: Mobocertinib 40mg capsules, Truxima (Rituximab) 500mg/50ml concentrate for solution for infusion vials, Votubia (Everolimus) 10mg tablets, Votubia (Everolimus) 2.5mg tablets, Votubia (Everolimus) 5mg tablets, Everolimus 2mg dispersible tablets, and Everolimus 5mg dispersible tablets. Removed: Benralizumab 30mg/1ml solution for injection pre-filled disposable devices.

  18. Added the following 4 medicines: Salbutamol 5mg/2.5ml nebuliser liquid unit dose vials, Salbutamol 1mg/1ml nebuliser liquid unit dose vials, Salbutamol 2mg/1ml nebuliser liquid unit dose vials, Tivozanib 1340mg capsules and Tivozanib 890mg capsules. Removed the following medicine: Bexarotene 75mg capsules.

  19. Added the following medicine to the list: Salbutamol 2.5mg/2.5ml nebuliser liquid unit dose vials. Removed the following medicine from the list: Amlodipine/Valsartan 10mg/160mg tablets; Amlodipine/Valsartan 5mg/80mg tablets.

  20. The following medicines have been added to the list: Alpelisib 50mg tablets, Alpelisib 200mg tablets, Alpelisib 150mg tablets, Alpelisib 50mg tablets and Alpelisib 200mg tablets, Darifenacin 7.5mg modified-release tablets, Darifenacin 15mg modified-release tablets, Rucaparib 200mg tablets, Rucaparib 250mg tablets, Rucaparib 300mg tablets, Benralizumab 30mg/1ml solution for injection pre-filled disposable devices.

  21. Added the following medicines to the list: (Trurapi 100 units/ml solution for injection 3ml pre-filled Solostar pens) Insulin aspart 100 units/ml solution for injection 3ml pre-filled disposable devices and Remdesivir 100mg powder for solution for infusion vials. Removed (Truxima 500mg/50ml concentrate for solution for infusion vials) Rituximab 500mg/50ml solution for infusion vials.

  22. Added the following medicine to the list: Reslizumab 100mg/10ml solution for infusion vials; Clopidogrel 300mg tablets; Eltrombopag 75mg tablets; (Remsima 100mg powder for concentrate for solution for infusion vials) Infliximab 100mg powder for solution for infusion vials. Removed the following medicine from the list: Glycopyrronium 44microgram inhalation powder capsules with device; Perampanel 10mg tablets; Perampanel 12mg tablets; Perampanel 2mg tablets; Perampanel 4mg tablets; Perampanel 500micrograms/ml oral suspension sugar free; Perampanel 6mg tablets; Perampanel 8mg tablets; Regadenoson 400micrograms/5ml solution for injection vials. Changed medicines (updated descriptions): Amlodipine/Valsartan 10mg/160mg to Amlodipine/Valsartan 10mg/160mg tablets; Amlodipine/Valsartan 5mg/160mg to Amlodipine/Valsartan 5mg/160mg tablets; Amlodipine/Valsartan 5mg/80mg to Amlodipine/Valsartan 5mg/80mg tablets; Choriogonadotropin to Choriogonadotropin 250micrograms/0.5ml solution for injection pre-filled syringes.

  23. Added the following medicine to the list: Perampanel 500micrograms/ml oral suspension sugar free.

  24. Added the following 16 medicines to the list: Perampanel 2mg tablets; Perampanel 4mg tablets; Perampanel 6mg tablets; Perampanel 8 mg tablets; Perampanel 10mg tablets; Perampanel 12mg tablets; Sodium tetradecyl sulfate 3% solution for injection vials; Sodium tetradecyl sulfate 3% solution for injection ampoules; Sodium tetradecyl sulfate 1% solution for injection ampoules; Sodium tetradecyl sulfate 0.5% solution for injection ampoules; Sodium tetradecyl sulfate 0.2% solution for injection vials; Ovitrelle 250mg/0.5ml solution for injection pre-filled syringes; Choriogonadotropin alfa 250mg/0.5ml solution for injection pre-filled syringes; Dornase alfa 2.5mg nebuliser liquid 2.5ml ampoules; Exenatide 2mg injection; Saxagliptin 2.5mg tablets; and Saxagliptin 5mg tablets. Removed the following 2 medicines from the list: Hemlibra 30mg/1ml solution for injection vials; Emicizumab 30mg/1ml solution for injection vials; and Epirubicin 200mg/100ml solution for infusion vials.

  25. Updated the list to correct a dosage error: changed Secukinumab 300mg/2ml solution for injection pre-filled disposable devices to Secukinumab 150mg/1ml solution for injection pre-filled disposable devices.

  26. Added the following medicines to the list: Bimatoprost 300micrograms/ml eye drops 0.4ml unit dose preservative free; (Truxima 500mg/50ml concentrate for solution for infusion vials) Rituximab 500mg/50ml solution for infusion vials; and Secukinumab 300mg/2ml solution for injection pre-filled disposable devices. Changed Basiliximab 10mg powder and solvent for solution for injection vials (1 vial) to Simulect 10mg powder and solvent for solution for injection vials (1 vial) (brand to generic).

  27. Removed the ‘NutropinAq 10mg/2ml solution for injection cartridges’ brand name from the following generic medicines: Regadenoson 400micrograms/5ml solution for injection vials; Omalizumab 150mg/1ml solution for injection pre-filled syringes; Fondaparinux sodium 1.5mg/0.3ml solution for injection pre-filled syringes; Simulect 20mg powder and solvent for solution for injection vials; Enfuvirtide 108mg powder and solvent for solution for injection vials; Upadacitinib 45mg modified-release tablets.

  28. Added the following medicines: NutropinAq 10mg/2ml solution for injection cartridges (Enfuvirtide 108mg powder and solvent for solution for injection vials); NutropinAq 10mg/2ml solution for injection cartridges (Fondaparinux sodium 1.5mg/0.3ml solution for injection pre-filled syringes); NutropinAq 10mg/2ml solution for injection cartridges (Omalizumab 150mg/1ml solution for injection pre-filled syringes); NutropinAq 10mg/2ml solution for injection cartridges (Regadenoson 400micrograms/5ml solution for injection vials); NutropinAq 10mg/2ml solution for injection cartridges (Simulect 20mg powder and solvent for solution for injection vials); NutropinAq 10mg/2ml solution for injection cartridges (Somatropin (rbe) 10mg/2ml solution for injection cartridges); NutropinAq 10mg/2ml solution for injection cartridges (Upadacitinib 45mg modified-release tablets). Removed the following medicines: Fondaparinux sodium 10mg/0.8 ml solution for injection, pre-filled syringe; Fondaparinux sodium 7mg/0.6 ml solution for injection, pre-filled syringe; Fondaparinux sodium 5mg/0.4 ml solution for injection, pre-filled syringe.

  29. Updated the list of medicines that can be moved through NIMAR, adding the following: Basiliximab 10mg powder and solvent for solution for injection vials (1 vial), Suboxone 2mg/500microgram sublingual tablets, Suboxone 8mg/2mg sublingual tablets, Hemlibra 30mg/1ml solution for injection vials, Glycopyrronium 44 microgram inhalation powder capsules with device, Levemir Innolet 100 units/ml solution for injection 3ml pre-filled pens, Insulatard penfill 100 units/ml suspension for injection 3ml cartridges, Insulatard Innolet 100 units/ml suspension for injection 3ml pre-filled pens, Insulatard 100 units/ml suspension for injection 10ml vials, Metformin/vildagliptin 1000mg/50mg tablets, Metformin/vildagliptin 850mg/50mg tablets, Nepafenac 3mg/ml eye drops and Toremifine 60mg tablets.

  30. Added the following medicines: Epirubicin 200mg/100ml solution for infusion vials; Streptokinase 250,000 unit powder for solution for infusion vials; and Streptokinase 1.5 million unit powder for solution for infusion vials. Removed: Spectrila 10,000 units powder for solution for injection; Zirabev 100mg/4ml solution for infusion vials; Zykadia 150mg tablets; Xigduo 5mg/1000mg tablets; Xigduo 5mg/850mg tablets; Indivina 1mg/2.5mg tablets; Indivina 2mg/5mg tablets; Insuman Comb 50 100units/ml suspension for injection 3ml cartridges; Insulin isophane biphasic human 50/50 100units/ml suspension for injection 3ml cartridges; Ibrance 100mg tablets; Ibrance 125mg tablets; Ibrance 75mg tablets; Onpattro 2 mg/mL concentrate for solution for infusion; Somavert 20mg powder and solvent for solution for injection vials; Kisqali 200mg tablets; Ozempic 0.25mg/0.19ml solution for injection 1.5ml pre-filled pens; Ozempic 0.5mg/0.37ml solution for injection 1.5ml pre-filled pens; and Metalyse 10,000unit powder and solvent for solution for injection vials.

  31. Updated to remove 'Forxiga 10mg tablets' and 'Dapagliflozin 10mg tablets' from the list.

  32. Uploaded a corrected CSV attachment, adding: 'Topotecan 4mg/4ml concentrate for solution for infusion vials' and removing: 'Topotecan 4mg powder for solution for infusion vials'.

  33. Updated list of medicines. Removed: Topotecan 4mg/4ml concentrate for solution for infusion vials. Added: Spectrila 10,000 units powder for solution for injection; Asparginase 10,000 units powder for solution for injection; Xigduo 5mg/1000mg tablets; Dapagliflozin 5mg/Metformin 1g tablets; Xigduo 5mg/850mg tablets; Dapagliflozin 5mg/Metformin 850mg tablets; Forxiga 10mg tablets; Dapagliflozin 10mg tablets; Topotecan 4mg powder for solution for infusion vials.

  34. Updated the CSV file of medicines that can be moved through NIMAR. Adding: Cell-based quadrivalent influenza vaccine (surface antigen, inactivated) suspension for injection 0.5ml pre-filled syringes; NeoRecormon 20,000units/0.6ml solution for injection pre-filled syringes; Epoetin beta 20,000units/0.6ml solution for injection pre-filled syringes; Ozempic 0.25mg/0.19ml solution for injection 1.5ml pre-filled pens; Semaglutide 0.25mg/0.19ml solution for injection 1.5ml pre-filled disposable device. Removing: Flucelvax Tetra vaccine suspension for injection 0.5ml pre-filled syringes; Influenza vaccine (surface antigen, inactivated) suspension for injection 0.5ml pre-filled syringes.

  35. Added the following to the list of medicines that can be moved through NIMAR: Amlodipine/Valsartan 10mg/160mg, Amlodipine/Valsartan 5mg/160mg, Amlodipine/Valsartan 5mg/80gm, Fluorouracil 2.5g/100ml solution for infusion vials, Palbociclib 100mg tablets, Palbociclib 125mg tablets, Palbociclib 75mg tablets, Fluenz Tetra vaccine nasal suspension 0.2ml unit dose, Flucelvax Tetra vaccine suspension for injection 0.5ml pre-filled syringes, Ozempic 0.5mg/0.37ml solution for injection 1.5ml pre-filled pens, Imvanex vaccine suspension for injection 0.5ml vials, Metalyse 10,000unit powder and solvent for solution for injection vials, Topotecan 4mg powder for solution for infusion vials.

  36. Added the following to the list: Bevacizumab 100mg/4ml solution for infusion vials, Ceritinib 150mg tablets, Enbrel paediatric 10mg powder and solvent for injection vials, Estradiol valerate 1mg / Medroxyprogesterone 2.5mg tablets, Estradiol valerate 2mg / Medroxyprogesterone 5mg tablets, Etanercept 10mg powder and solvent for injection vials, Ibrance 75mg capsules, Ibrance 100mg capsules, Ibrance 125mg capsules, Indivina 1mg/2.5mg tablets, Indivina 2mg/5mg tablets, Kisqali 200mg tablets, Lapatinib 250mg tablets, Palbociclib 75mg capsules, Palbociclib 100mg capsules, Palbociclib 125 mg capsules, Pegvisomant 20mg powder and solvent for solution for injection vials, Ribociclib 200mg tablets , Somavert 20mg powder and solvent for solution for injection vials, Tyverb 250mg tablets (84 tablet), Zirabev 100mg/4ml solution for infusion vials and Zykadia 150mg tablets.

  37. Added to the list: Onpattro 2 mg/mL concentrate for solution for infusion; Patisiran 2 mg/mL concentrate for solution for infusion.

  38. Added Everolimus 3mg dispersible tablets sugar free, Nilotinib 150mg capsules, Pazopanib 200mg tablets, and Pazopanib 400mg tablets.

  39. Updated to remove Glucagon 0.5mg solution for injection in pre-filled pen from the list.

  40. Added Silver Sulfadiazine Cream 1%, Glucagon 0.5mg solution for injection in pre-filled pen, Glucagon 1mg solution for injection in pre-filled pen. Removed Estradiol 0.06% gel (750microgram per actuation).

  41. Replaced spreadsheet with updated version with the following listing: 'Fondaparinux sodium 7.5mg/0.6ml solution for injection, pre-filled syringe'.

  42. Added fondaparinux 5mg, 7mg and 10mg to the list of medicines that can be moved through NIMAR.

  43. Added bexarotene 75mg capsules to and removed eltrombopag 75mg capsules and thiopental from the list of medicines that can be moved through NIMAR.

  44. Replaced spreadsheet with updated version listing Buccolam as the brand name for Midazolam.

  45. Added Acetylcysteine, Canagliflozin, Eltrombopag, Estradiol, Insulin isophane, Midazolam, Progesterone and Topotecan to the list of medicines that can be moved through NIMAR.

  46. Added Etanercept 50mg/1ml, Somatropin (rbe) (5mg/1.5ml, 10mg/1.5ml, 15mg/1.5ml) and Thiopental 500mg powder to the list of medicines that can be moved through NIMAR.

  47. Added 'Cobimetinib 20mg tablets' to the list of medicines that can be moved through NIMAR.

  48. Added 2 new lines to the list: sodium chloride 0.18% + glucose 4% infusion bags and sucralfate 1g/5ml liquid.

  49. First published.