Guidance

Guidance on the use of (Q)SAR models to predict genotoxicity

COM recommendations for an evaluation of genotoxicity using (Q)SAR models.

Documents

Details

This guidance statement outlines Committee on Mutagenicity of Chemicals in Food, Consumer Products and the Environment (COM) recommendations for an evaluation of genotoxicity using (Q)SAR models, including the selection of the (Q)SAR model by assessment and justification of the model and reporting of (Q)SAR predictions.

The information in this document is intended to be a resource for regulatory authorities, risk assessors, other scientists, as well as (Q)SAR model developers and (Q)SAR users.

Updates to this page

Published 23 February 2026

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