Guidance

Known supply problems with animal medicines

Reported problems with the supply of an animal medicine and the date when the issue is expected to be resolved.

Companies must report supply problems to the Veterinary Medicines Directorate when product shortages are identified. A shortage occurs when supply of a veterinary medicine does not meet national demand.

Information on product shortages where there is no known alternative product is published here. In such instances, vets may prescribe using the cascade. Vets are reminded that it is their responsibility to apply use of the cascade appropriately based on clinical need.

More information can be found on The Cascade: Prescribing unauthorised medicines page.

For non-UK products vets must apply for a certificate to import a Veterinary Medicine into the UK.

For information on manufacturers of extemporaneous products, please read the ManSA Register

Supply problems exist with the following products

Vaccines for Newcastleimmunisation Diseaseagainst VirusMycoplasma bovis

The VMD ishave awarereceived an unprecedented number of theSIC followingapplications shortagesto affectingimport NDV‘Myco vaccines:B One Dose’.

  • PoulvacIt NDWshould (GB:be 42058/5203noted &that NIapplications 60021/3081):for Outthis ofproduct stockshould inonly Greatbe Britainsubmitted (GB)should untilthere Augustbe 2026;no notsuitable marketedUK inauthorised Northernproduct Ireland (NI).available.

  • AvinewDetails Neoof EffervescentUK Tabletsauthorised forvaccines Chickensindicated andfor Turkeysimmunisation (GB:against 08327/5043Mycoplasma &bovis NI:infection 08327/5043):can Outbe offound stockon inthe Product GBInformation withDatabase.

    Veterinary noreplacement confirmedfluids restockfor date;infusion

    The notVMD marketedis inaware NI.

  • Nobilisof NDa Cloneshortage 30of Liveveterinary Lyophilisatereplacement fluids for Oculonasalinfusion.

    We Suspension/Useunderstand inthat Drinkingwhilst Watersome (ChickensUK andauthorised Turkeys)veterinary (GB:fluids 06376/5047remain &available, NI:these 06376/3049):are Out of stock in bothlimited GBquantities. For anddetails NIof untilthe Junesupply 2026.

  • VAXXONsituation NDfor CLONEindividual (LyophilisateUK andauthorised Solventproducts, forplease Oculonasalcontact Suspension,the Chickens)relevant (NI:Marketing EU/2/24/326/001-004):Authorisation AuthorisedHolder inor NIyour only;usual currentlywholesaler.

    While outthere ofare stocksupply issues with nosome confirmedreplacement returnfluids, date.

  • AviProvets NDmay C131consider Lyophilisateuse forof Suspensionalternative (Chickensproducts andunder Turkeys)the (GB:Cascade, 52127/5099however &vets NI:should 52127/3034):make Expectedevery effort to befirst relaunchedobtain ina JuneUK 2026.authorised product.

WeDue haveto receivedthe confirmationclinical thatneed thefor followingthis vaccinescategory areof currentlyproduct, available:

  • Avishieldthe NDVMD B1,has Lyophilisaterecently forassessed Oculonasalthe Suspension/Usefollowing inproducts Drinkingfor Waterimport (Chickens)under (GB:the 61812/5001Special &Import NI: 61812/3001)Scheme:

  • Avishield

    ProductCountry of OriginMA Numbers
    Ringer NDlattato Lyophilisatesoluzione forper Oculonasalinfusione Suspension/Useendovenosa inper Drinkingtutte Waterle (ChickensspecieItaly102322029, and102322043, Turkeys)102322068, (GB:102322031, 61812/5000102322070, &102322056, NI:102322082, 61812/3000)

    Vaccines102322094, containing102322118, additional102322120, components102322132, are102322144, also102322157

    Vetivex authorisedsolution andau mayringer belactate available.

    Whilepour supplyperfusion constraintspour arebovins affectingchevaux severalchiens NDVet vaccines,chats

    FranceFR/1/2198629 1/2013

    To address the shortage, veterinary surgeons may consider the use of alternativethe above products under the Cascade.cascade However,once everythe effortnecessary shouldimport firstcertificate behas madebeen toobtained. sourceIf aveterinary UK-authorisedsurgeons product. Veterinarians are remindedaware thatof itany remainsother theiralternative responsibilityproducts, tothey applycan thesubmit Cascadean appropriately,SIC basedapplication onfor clinical need.these.

    Vaccines for immunisation against Mycoplasma bovis

    TheAs VMDa havereminder, receivedwhere anauthorised unprecedentedproducts numberare oftemporarily SICunavailable applicationsvets to import ‘Myco B One Dose’.

    It should beconsider notedthe thatlikely applicationsquantities forneeded thisand productpurchase shouldappropriately. As onlysoon beas submittedan should there be no suitable UK authorised product available.

    Detailsis ofavailable UKagain, authorisedvets vaccinesare indicatedexpected forto immunisationuse againstthis Mycoplasmaeven bovisif infectionthey canstill behave foundstocks onof the Productunauthorised Information Database.products.

    Vaccines for immunisation against equine influenza and tetanus

    The VMD have been informed that there is now returned supply of UK authorised equine flu and tetanus vaccines.

    The VMD will no longer accept applications to import alternative products, including Vetera 2XP licensed in the USA.

    Vaccine for immunisation against ringworm

    Following the granting of a marketing authorisation, the VMD have been informed that there is availability of Trichovec, Lyophilisate and Solvent for Suspension for Injection for Cattle (Vm 51609/3000 and 51609/5000).

    Therefore the VMD will no longer issue import certificates for ‘Trichoben’ as authorised in the Czech Republic and Netherlands.

    Products containing acepromazine for anaesthetic premedication, tranquilisation and sedation in horses

    Following the granting of a marketing authorisation the VMD have been informed that there is availability of a 10mg/ml acepromazine solution for injection:

    • AceSedate 10mg/ml solution for injection for horses Vm: 25296/4008

    Therefore the VMD will no longer issue import certificates for alternative acepromazine products, including:

    • Calmivet solution for injection (5mg/ml), licensed in France
    • Vetranquiol 1% solution for injection (10mg/ml), licensed in Germany and Netherlands

    This will take effect immediately.

    Existing certificates will remain valid until their date of expiry, however veterinary surgeons are reminded to apply the Cascade responsibly and use UK authorised product where available.

    2mg/ml presentations are also available. Information on authorised acepromazine-containing products is available on the VMD’s Product Information Database.

    Viper Venom Antiserum for veterinary use (adder bite antivenom)

    There is no viper venom antiserum licensed in the UK for the treatment of adder bites in animals.

    VMD accept applications to import European Viper Antiserum from Biomed (Poland) and Institute of Immunology, Zagreb (Croatia).

    Before submitting an application contact the relevant manufacturer to ensure they are able to supply the quantity of product you wish to import.

    Contact details of the approved manufacturers

    BIOMED Warsaw
    Wytwornia Surowic i szczepionek BIOMED Ltd
    Ul. Chelmska 30/34
    00-725 Warsaw
    Phone. 022 841 4071

    Institute of Immunology
    Rockefellerova 2
    10000 Zagreb, Croatia
    Phone +385 1 46 84 500

    In urgent cases the antivenom may be supplied, purchased and used prior to the special treatment certificate being obtained from the VMD. This is a special dispensation made for this clinical condition only.

Updates to this page

Published 30 September 2014

Last updated 1211 MayFebruary 20262025 + show hide all updates" href="#full-history">+ show all updates
    1. Updated to include NDV vaccine shortage information.

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